Search on: JUNCTION, CELL-MATRIX ADHERENS 
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Descriptor English:   Focal Adhesions 
Descriptor Spanish:   Adhesiones Focales 
Descriptor Portuguese:   Adesões Focais 
Synonyms English:   Adherens Junction, Cell-Matrix
Adherens Junctions, Cell-Matrix
Adhesion Plaque
Adhesion, Focal
Adhesions, Focal
Cell Matrix Adherens Junctions
Cell-Matrix Adherens Junction
Contact, Focal
Contacts, Focal
Focal Adhesion
Focal Contact
Junction, Cell-Matrix Adherens
Junctions, Cell-Matrix Adherens
Plaque, Adhesion
Plaques, Adhesion
Adhesion Plaques
Cell-Matrix Adherens Junctions
Focal Contacts  
Tree Number:   A11.284.149.165.165.285
Definition English:   An anchoring junction of the cell to a non-cellular substrate. It is composed of a specialized area of the plasma membrane where bundles of the ACTIN CYTOSKELETON terminate and attach to the transmembrane linkers, INTEGRINS, which in turn attach through their extracellular domains to EXTRACELLULAR MATRIX PROTEINS. 
See Related English:   Cell Adhesion
 
History Note English:   2001 
Allowable Qualifiers English:  
CH chemistry CL classification
DE drug effects EN enzymology
GE genetics IM immunology
ME metabolism MI microbiology
PS parasitology PA pathology
PH physiology RE radiation effects
SE secretion TR transplantation
UL ultrastructure VI virology
Record Number:   35265 
Unique Identifier:   D022001 

Occurrence in VHL: 		 

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